Derivatization on Solid Supports: An Alternative Method for Solution Derivatization of Amines in Several Matrices

Agilent Bond Elut C18 gave the best results is this effective application of derivatizing aliphatic and biogenic amines on SPE versus solution derivatization. Published by Springer. Forensics and toxicology Development and validation of a gas chromatography-mass spectrometry method for the simultaneous determination of buprenorphine, flunitrazepam and their metabolites in rat plasma: application to the pharmacokinetic study Journal of Chromatography B, 807, 335-342 (2004) S. Pirnay et al. Tags Bond Elut Certify, HP-5ms, forensics and toxicology Abstract An Agilent J&W HP-5ms GC column was used for analysis of opioid analgesics extracted from plasma samples with Agilent Bond Elut Certify. Published by Elsevier B. V. Hair testing and self-report of cocaine use Forensic Science International, 215, 77-80 (2012) Claudia Vignali et al. Tags Bond Elut Certify, forensics and toxicology Abstract Hair was tested for amphetamines, cocaine, and opiates using Bond Elut Certify sample prep with GC/MS of derivatized samples, with extremely low LODs of 0.01 to 0.03 ng/mL and good recoveries. Published by Elsevier B. V.Hair was tested for amphetamines, cocaine, and opiates using Bond Elut Certify sample prep with GC/MS of derivatized samples, with extremely low LODs of 0.01 to 0.03 ng/mL and good recoveries. Published by Elsevier B. V. Development of a Liquid Chromatographic Method for the Simultaneous Determination of Six Benzodiazepines in Human Plasma After Solid-Phase Extraction Analytical Letters, 43, 1075-1084 (2010) Purificación Fernández et al. Tags Bond Elut NEXUS, Bond Elut Certify, forensics and toxicology Abstract A simple and fast procedure is presented for the simultaneous determination of alprazolam, bromazepam, diazepam, lorazepam, lormetazepam, and tetrazepam in human plasma. The drugs were isolated by solid-phase extraction, and the subsequent analysis was carried out by highperformance liquid chromatography coupled with a diode-array detector (HPLC-DAD). This allowed recoveries of around 90% to be obtained with good sensitivity, selectivity, and resolution of the eluting peaks. The detector response at 230 nm was linear within the benzodiazepine concentration range of 20–4000 ng/mL in human plasma, with values of less than 6.7% and 5.4% for precision and accuracy, respectively. ©2013 Taylor & Francis. Materials testing and research o-Phthalaldehyde–N-acetylcysteine polyamine derivatives: formation and stability in solution and in C18 supports Sciences and Applications, 759, 265-297 (2001) P. Campı́ns-Falcó et al. Tags Bond Elut PPL, Bond Elut C2, C8 and C18, Bond Elut Certify, Hypersil ODS, materials testing and research Abstract On SPE derivatization of polyamines with OPA, Agilent Bond Elut C18 was the best although recovery could be improved. Published by Elsevier B. V. www.agilent.com/chem For Forensic Use. Agilent shall not be liable for errors contained herein or for incidental or consequential damages in connection with the furnishing, performance, or use of this material. Information, descriptions, and specifications in this publication are subject to change without notice. © Agilent Technologies, Inc., 2015, 2017 Printed in the UK 28 June, 2017